Multi-drug-resistant tuberculosis in Covid-19 pandemic period, Dushanbe
Abstract
Aim. To determine changes in the demographic, clinical and epidemiological characteristics of patients with multidrug-resistant tuberculosis during the COVID-19 pandemic.
Materials and methods. A cross-sectional study included patients with multidrug-resistant tuberculosis (MDR TB) registered in Dushanbe before (2017-2019 нуфкы) and during the COVID-19 pandemic (2020-2021).
Research results and discussion. The mean age of patients before the COVID-19 pandemic was 36.5±16.9 years (1.7-79.4), in the COVID-19 period 34.4±17 years (2.9-80.2). During the pandemic, there was a statistically significant increase in the proportion of workers among MDR TB patients compared with the unemployed (OR = 1.4; 95% CI 1.02-1.91; p = 0.05), an increase in the proportion of patients with lung destruction in both newly diagnosed (OR 3.4; 95% CI 1.99–5.87; p<0.001) and previously treated patients (OR 4.2; 95% CI 1.38–12.99; p =0.002,), increased in extrapulmonary tuberculosis registration (OR=1.7; 95% CI 1.34-2.22; p<0.001), which indicates an unfavorable epidemiological situation in terms of MDR-TB. There were no statistically significant changes in the registration of concomitant diseases.
Conclusion. It is recommended to improve the implementation of TB infection prevention and control measures at all levels, strengthening the early detection of TB and MDR TB patients by primary health care workers.
About the Authors
Z. H. Tilloeva
State Institution “City Disinfection Station”
Tajikistan
Tajikistan
Tilloeva Zulfiya Khaibulloevna – epidemiologist.
Dushanbe, A. Donish avenue 16; Tel: +(992) 934 47 73 53
A. S. Mirzoev
State Institution “Research Institute of Preventive Medicine of Tajikistan”; State Educational Institution “Institute of Postgraduate Education in Healthcare of the Republic of Tajikistan”
Tajikistan
Tajikistan
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Review
For citations:
Tilloeva Z.H., Mirzoev A.S. Multi-drug-resistant tuberculosis in Covid-19 pandemic period, Dushanbe. Herald of the medical and social institute of Tajikistan. 2022;(4):43-53. (In Russ.)
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