Microbiological characteristics of causes of hospital-hospital infections and development of a method for diagnosis of hospitalized strains

Objective: to establish the etiological structure of microorganisms isolated from nosocomial infections in the region, to present the microbiological characteristics of pathogens of nosocomial infections and to develop a method for indicating hospital strains. Material and methods: a retrospective analysis of data for the past 5 years was conducted. The etiologic structure of nosocomial infections was studied in clinical material obtained from parents, newborns, and postoperative patients, as well as in swabs from environmental objects in healthcare facilities. Identificationof hospital strains was carried out by determining the sensitivity of strains to antibiotics, compiling and comparing antibiograms of bacterial cultures isolated from patients and from environmental objects. Results: the incidence of nosocomial infections showed a downward trend (T sn = 8.6), consistent with the general trend in Uzbekistan as a whole.In isolates of S. aureus, E. coli, P. aeruginosa, and K. pneumoniae, a high frequency of isolation of multidrug-resistant strains was observed, which retained sensitivity only to drugs of the fluoroquinolone group. Conclusions: 1. The incidence of nosocomial infections showed a downward trend (T sn = 8.6), consistent with the general trend in Uzbekistan as a whole. 2. In isolates of S. aureus, E. coli, P. aeruginosa, and K. pneumoniae, a high frequency of isolation of multidrug-resistant strains was observed, which retained sensitivity only to drugs of the fluoroquinolone group.

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