Study of differentiated approaches to therapy of involutionary changes in facial skin
Abstract
Objective: to investigate the effectiveness of skinbooster injection in patienys with age-related facial skin changes according to the data of immediate and long-term results. Material and methods: the work was carried out in the SEI“City clinical hospital of skin diseases” c.Dushanbe in the period 2021-2024 years. The study included 96 women permanently residing in Dushanbe, with chrono and photo-aging aged 35 to 65 years(average age 49.54+ 7.57 years) of applying for cosmetology help. The degree of skin aging was determined by visual scale MERZ, the R. Glogau scale used for photo aging and to determine the total aging index the GAIS scale. Skinboosters were injected with a multi-puncture technique in a short linear 0.01-0.02 milliliter an interval between injections from 0.5 to 1 cm. Patients underwent 3 procedures for the introduction of skin boosters in the amount of 2 milliliters with an interval of 1 month D01-M01-M02. Results: our study, which includes several stages of analysis of methods, presents the immediate (3-5 months) and long-term results(12 month from the start therapy). At the first stage, clinical evaluation of patients with involutional skin ganges(ICS)was carried out. At the initial signs of photoaging (stages I and II), skin booster injections can be used, at moderate and severe stages to obtain a pronounced and lasting effect, it is necessary to strengthen filler therapy in combination with hardware methods (fractional erbium or CO2 laser, RF technology, IPL, Alter therapy, etc.). At the second stage, distribution was prowoked patients are divided into two therapeutic groups. The examined women from group I, using non-surgical methods of cosmetic correction, looked younger than their peers from group II, who applied for cosmetic help for the first time. At the third stage of the study, the clinical efficacy of skinbooster injections was studied according tj the data of immediate and long-term results of use (5 and 12months), with chrono-aging in women in two groups. Research results demonstrated a significant improvement in the quality of the facial skin after injection with staunlized hyaluronic acid (sGC) with liloccann injection methods. Recommended, so that skinbooster therapy with sGC is repeated after 6-12 months for optimal results of correction of signs of photoaging. Conclusion: our modest experience of a differentiated approach of step by step shading course treatment using skinbooster injections, meets modern requirements for entering into daily dermatological practice aimed at improving the quality of medical and cosmetological assistance provided to women.
About the Author
Z. N. SohibovaTajikistan
Sohibova Zyfnuna Nazirovna - Candidate of Medical Sciences, Associate Professor, Head of the Department of Histology
References
1. Zhukova O.V., Kruglova L.S., Frigo N.V. Method of aesthetic correction of involutional changes in the facial skin. Clinical dermatology and venereology. 2018;17(2):114-117.
2. Korolkova T.N., Shepilova I.A., Kalmykova N.V. Effect of chemical peels with retinoids on immunohistochemical parameters of the skin. Clinical dermatology and venereology. 2019;(2):210-216.
3. Alenichev A. Yu., Kruglova L. S., Fedorov S. M., Sharypova I. V. Evaluation of the effectiveness of microneedle RF therapy in the correction of involutional changes in the skin of the face and neck. Physiotherapist. 2017; (4):4-13.
4. Sohibova Z.N. Age related changes in the content of glycosaminoglycans, protein and nucleic acids in the skin of women / IV Annual Republican Scientific and Practical Conference of the NOU “Medical social institute of Tajikistan “ on the topic “Strategy for the Development of Medical and Social Sciences in the Republic of Tajikistan, Experience, Problems and Solutions”. Dushanbe. 2024:158 159. 2024:158-159.
5. Sohibova Z.N. Skin changes in chronological and photoinduced aging of women / Republican scientific and practical conference (3rd annual) of the NOU “Medical social institute of Tajikistan “ on the topic “Actual problems of clinical and social medical science and ways of its development in the Republic of Tajikistan” with the participation of foreign specialists. 2023:78-79.
6. Kruglova L.S., Ikonnikova E.V. Skin hyper pigmentation: modern views on etiology and pathogenesis. Russian Journal of Skin and Venereal Diseases. 2017;20 (3):178-183.
7. Sharova A.A., Pavlenko O.Yu. Correction of aesthetic defects of some areas of the body with preparations for injection plastic surgery // Injection methods in cosmetology. 2015;3:114-124.
8. Obagi Z.E. The Art of Skin Healing: Restoration and Rejuvenation. Scientific Foundations of Clinical Practice / Zein E. Obagi; [translated from English by A.A. Polyanskaya, O.V. Stafinova]. Moscow: Practical Medicine. 2016:300
9. Trakatelli M, Bylaite Bucinskiene M, Correia O et al.Clinical assessment of skin phototypes: watch your words! Eur J Dermatol. – 2017. Dec 1;27(6):615 619. doi: 10.1684/ejd.2017.3129.
10. Hertz Kleptow D, Hanschmann A, Hofmann M, Reuther T, Kerscher M. Facial skin revitalization with CPM® HA20G: an effective and safe early intervention treatment. 12, 563—572: 2019
11. Dzybova E., Kruglova L., Alenichev A. Combined use of micro needling RF treatment with injections of Platelet Rich Plasma activated by autologous thrombin in aesthetic medicine: P0120 – 14th EADV Spring Symposium, Brussels, Belgium, 2017.
12.
Review
For citations:
Sohibova Z.N. Study of differentiated approaches to therapy of involutionary changes in facial skin. Herald of the medical and social institute of Tajikistan. 2025;(3):60-69. (In Russ.)




